Is elemental 028 vegan?
By
Dr Anny Manrich (PhD)
Author bio
Dr Anny Manrich PhD is a food Engineer with expertise in Food Technology, Natural Polymers, Edible Films, Enzymes, and Nanotechnology. She writes and reviews content on these topics.
Dr Anny Manrich’s Highlights:
- Research and Technology at the Brazilian Agricultural Research Corporation
- PhD in Chemical Engineering with a focus on Biochemistry at the Federal University of Sao Carlos/ Brazil and a one-year scholarship at the Technical University of Munich/ Germany
- Bachelor of Food Engineering at the University of Campinas/ Brazil and a one-year scholarship at the Technical University of Munich/ Germany
“To solve a problem, global vision and multifactorial understanding are necessary. Therefore, in addition to expertise, one should seek multidisciplinary thinking connected with science and reality” – Dr Anny Manrich, PhD.
Professional Experience:
Dr Anny Manrich’s Experience Joining the Brazilian Agricultural Research Corporation, as soon as she completed her doctorate,
Dr Anny Manrich has worked on several projects, including the more than three-year partnership project with BRF, a major food producer in Brazil. As a postdoctoral fellow.
Dr Anny Manrich has also contributed to several business consultancies and research projects of the National Nanotechnology Laboratory System in areas such as food technology, fibres, films and coatings and Nanotechnology; in a very determined way, having a great team relationship, being creative and committed.
Growing concerns about the safe introduction of nanomaterials into today’s life emphasises the need to create regulatory documentation in front of characterising, using and testing them. Dr Anny Manrich worked for two years on a characterization project for nanoscale materials, with the aim of exploring their possible health effects.
Despite not having specific academic training in packaging or polymeric films, Dr Anny Manrich works at the Brazilian Agricultural Research Corporation in areas of edible and biodegradable films produced from agricultural waste and in the development of films with greater resistance to water, having articles published in renowned scientific journals, which demonstrates her multidisciplinary understanding and creativity.
In addition, she worked for four years as a consultant to a food company to develop a line of snacks that are healthy and that add functional ingredients, physiologically active compounds that bring health benefits, made from fruits and vegetables, enabling diet improvement, disease prevention and reduction of nutritional deficiencies.
Dr Anny Manrich participated as a member of the examination board for two Master’s exams and one PhD exam at the Department of Chemical Engineering of the Federal University of São Carlos.
Education:
- 2001 Bachelor in Food Engineering at the State University of Campinas, Brazil
- 1999 One year scholarship at the Technical University of Munich
- 2004 Master in Chemical Engineering at the Federal University of São Carlos, Brazil
- 2012 PhD in Chemical Engineering at the Federal University of São Carlos, Brazil
- 2010 One year scholarship at the Technical University of Munich
The main publications of Dr. Anny Manrich are:
Articles
Manrich, A., Moreira, F. K., Otoni, C. G., Lorevice, M. V., Martins, M. A., & Mattoso, L. H. (2017). Hydrophobic edible films made up of tomato cutin and pectin. Carbohydrate Polymers, 164, 83-91.
Mendes, J. F., Norcino, L. B., Martins, H. H. A., Manrich, A., Otoni, C. G., Carvalho, E. E. N., … & Mattoso, L. H. C. (2020). Correlating emulsion characteristics with the properties of active starch films loaded with lemongrass essential oil. Food Hydrocolloids, 100, 105428.
Norcino, L. B., Mendes, J. F., Natarelli, C. V. L., Manrich, A., Oliveira, J. E., & Mattoso, L. H. C. (2020). Pectin films loaded with copaiba oil nanoemulsions for potential use as bio-based active packaging. Food Hydrocolloids, 106, 105862.
Manrich, Anny, et al. Immobilization of trypsin on chitosan gels: Use of different activation protocols and comparison with other supports. International Journal of Biological Macromolecules 43.1 (2008): 54-61.
Manrich, Anny; Komesu, Andrea ; Adriano, Wellington Sabino; Tardioli, Paulo Waldir ; Giordano, Raquel Lima Camargo . Immobilization and Stabilization of Xylanase by Multipoint Covalent Attachment on Agarose and on Chitosan Supports. Applied Biochemistry and Biotechnology, v. 161, p. 455-467, 2010.
Mendes, J. F., Martins, J. T., Manrich, A., Neto, A. S., Pinheiro, A. C. M., Mattoso, L. H. C., & Martins, M. A. (2019). Development and physical-chemical properties of pectin film reinforced with spent coffee grounds by continuous casting. Carbohydrate polymers, 210, 92-99..
Milessi, T. S., Kopp, W., Rojas, M. J., Manrich, A., Baptista-Neto, A., Tardioli, P. W., … & Giordano, R. L. (2016). Immobilization and stabilization of an endoxylanase from Bacillus subtilis (XynA) for xylooligosaccharides (XOs) production. Catalysis Today, 259, 130-139.
Mendes, J. F., Norcino, L. B., Manrich, A., Pinheiro, A. C. M., Oliveira, J. E., & Mattoso, L. H. C. (2020). Development, physical‐chemical properties, and photodegradation of pectin film reinforced with malt bagasse fibers by continuous casting. Journal of Applied Polymer Science, 137(39), 49178.
Mendes, J. F., Martins, J. T., Manrich, A., Luchesi, B. R., Dantas, A. P. S., Vanderlei, R. M., … & Martins, M. A. (2021). Thermo-physical and mechanical characteristics of composites based on high-density polyethylene (HDPE) e spent coffee grounds (SCG). Journal of Polymers and the Environment, 29, 2888-2900..
Mendes, J. F., Norcino, L. B., Martins, H. H., Manrich, A., Otoni, C. G., Carvalho, E. E. N., … & Mattoso, L. H. C. (2021). Development of quaternary nanocomposites made up of cassava starch, cocoa butter, lemongrass essential oil nanoemulsion, and brewery spent grain fibers. Journal of Food Science, 86(5), 1979-1996.
Manrich, A., Martins, M. A., & Mattoso, L. H. C. (2021). Manufacture and performance of peanut skin cellulose nanocrystals. Scientia Agricola, 79.
Nascimento, V. M., Manrich, A., Tardioli, P. W., de Campos Giordano, R., de Moraes Rocha, G. J., & Giordano, R. D. L. C. (2016). Alkaline pretreatment for practicable production of ethanol and xylooligosaccharides. Bioethanol, 2(1)..
Manrich, Anny, de Oliveira, J. E., Martins, M. A., & Mattoso, L. H. C. Physicochemical and Thermal Characterization of the Spirulina platensis. J. Agric. Sci. Technol. B, v. 10, p. 298-307, 2020.
Book Chapter
Terra, I. A. A., Aoki, P. H., Delezuk, J. A. D. M., Martins, M. A., Manrich, A., Silva, M. J., … & Miranda, P. B. (2022). Técnicas de Caracterização de Polímeros. Nanotecnologia Aplicada a Polímeros, 614.
Conference Papers
Ferreira, L. F., Luvizaro, L. B., Manrich, A., Martins, M. A., Júnior, M. G., & Dias, M. V. (2017). Comparação da estabilidade de suspensões poliméricas de amido/tocoferol e quitosana/tocoferol. In: CONGRESSO BRASILEIRO DE POLÍMEROS, 14., 2017, Águas de Lindóia, SP.
Manrich, A., Hubinger, S. Z., & Paris, E. C. (2017). Citotoxicidade causada por nanomateriais: avaliação do micronúcleo. In: WORKSHOP DA REDE DE NANOTECNOLOGIA APLICADA AO AGRONEGÓCIO, 9., 2017, São Carlos. Anais… São Carlos: Embrapa Instrumentação, 2017. p. 655-658.
Manrich, Anny, et al. Immobilization and Stabilization of Xylanase by multipoint covalent attachment on Glyoxyl Agarose Support. The 31st Symposium on Biotechnology for Fuels and Chemicals. 2009.
Manrich, Anny, et al. Application of immobilized xylanase on hydrolysis of soluble wood hemicelluloses after using microwave and organosolv pre-treatments. The 32nd Symposium on Biotechnology for Fuels and Chemicals. 2010.
You can view some of Dr Anny’s work below and links to her professional profile.
Research Gate: https://www.researchgate.net/profile/Anny-Manrich-2
Scopus: https://www.scopus.com/authid/detail.uri?authorId=23103497100
Google Scholar: https://scholar.google.com/citations?hl=en&user=Ea9qpr0AAAAJ
Linkedin: https://br.linkedin.com/in/anny-manrich-20693129
In this brief guide, we will answer the query, “Is elemental 028 vegan?” and will discuss precautions and dosage recommendations for elemental 028.
Is elemental 028 vegan?
No, elemental 028 is not vegan. Elemental 028 is a mixture of amino acids which may be derived from animal products that’ why it is not suitable for vegans.
What is elemental 028?
Medical supervision is required for the usage of Elemental 028 Extra Liquid, which is a Food for Special Medical Purposes. Nutritionally complete and based on amino acids, Elemental 028 Extra Liquid is formulated to give comprehensive nutritional support or dietary supplements to help manage situations when the GI tract is severely impaired. Sugars and other sweeteners are used. Child-to-adult age range: 1-year-old and above. From the age of five, this product may be used as a single source of nourishment. Children above the age of one may use this product as a supplement.
One of the main uses of Elemental 028 is the treatment of inflammatory bowel disease, which is a chronic disease mediated by the immune system and characterized by the inflammation of the gastrointestinal tract. Inflammatory bowel disease includes Crohn’s disease as well as ulcerative colitis. One of the possible treatments for this pathology is a change in the type of diet. One of the potential changes in diet is the use of enteral nutrition, which is based on the administration of enteral foods/ formulas through different means. These foods are nutritionally-complete liquid mixtures of pre-digested foods that have carbohydrates such as simple sugars, fats such as different types of oils, and nitrogen as protein, along with vitamins and minerals (1).
When to use elemental 028?
In cases when the gastrointestinal system is severely impaired, Elemental 028 Extra Liquid is an elemental diet that may give comprehensive nutritional support or extra feeding.
Administration of enteral nutrition has long been considered the standard of care for nutrition support among patients unable to meet energy and protein requirements orally in efforts to prevent undesirable outcomes associated with malnutrition. Elemental and semi-elemental formulas are often used among patients with malabsorptive disorders and/or those having difficulties absorbing and digesting standard polymeric formulas. This is the case of patients suffering from inflammatory bowel disease, Crohn’s disease and ulcerative colitis (2).
Crohn’s disease Intractable malabsorption, intestinal fistulas, radiation enteritis, and food allergies are all symptoms of short bowel syndrome.
Precautions
· Not for intravenous usage
· Must only be used under physician supervision
Contradictions
· Gastrointestinal failure
· Complete intestinal failure
· Major intra-abdominal sepsis
Direction to use
Elemental 028 Extra Liquid is best given as a cold drink and should be used within 24 hours after opening. The amount of feed should be set by a clinician or dietician solely and is depending on the patient’s age, body weight, and medical condition.
What exactly is an “elemental diet?”
Nutritionally complete formulae in “pre-digested” form constitute an elemental diet. In liquid or powder form, these formulas are designed to be blended with water and sipped.
Protein, fat, and carbohydrates in elemental formulations have previously been broken down into their amino acids, fatty acids, and sugars for ease of digestion and absorption. Vitamins and minerals are also found in them. Macronutrients are hydrolyzed to improve absorption. Carbohydrate may be included from sources such as hydrolyzed cornstarch, maltodextrin, or fructose; protein from free amino acids and dipeptides or tripeptides (hydrolyzed casein, whey, or soy protein isolate); and lipid from fatty acid esters or medium-chain triglycerides (2).
For this reason, an elemental diet enables your digestive system to relax without compromising your nutritional intake. Carbohydrates and protein make up the bulk of most basic formulae since fat is difficult to digest. People with severe digestive difficulties are typically advised on an elemental diet.
Elemental formulas differ from polymeric formulas, which are designed to mimic a general diet by providing carbohydrate, protein, and fat in non-hydrolyzed forms. Common sources of carbohydrate in enteral formulas include corn maltodextrin and corn syrup solids. Common sources of protein include sodium and calcium caseinates and soy protein isolates. Lipid sources are usually canola, soybean, and/or safflower oil. Normal digestion function is typically required for polymeric formulas (2).
How does an elemental diet work?
People on an elemental diet often don’t eat anything other than elemental formulations. Other than water and simple tea, the only other liquids that may be consumed are water and water. It is possible to provide elemental formulae through a feeding tube or intravenous treatment, as well as combine them with water and drink them.
To avoid cramping and gastrointestinal discomfort, healthcare practitioners typically advise consuming elemental formulae at a gradual speed. It’s possible to get a professionally produced elemental formula that provides all the calories and nutrients you need. These may either be purchased over the counter or prescribed by a doctor.
When following an elemental diet, a qualified dietitian and a medical practitioner are usually always involved in making recommendations on the sort of formula and how much to consume.
Elemental formulas provide the majority of a person’s daily nutrition, although some individuals may only obtain a fraction of their daily requirements through formulas and the remainder from solid meals. Half- or semi-elemental diets are often referred to in these cases.
People who have had a large portion of their intestine removed may continue on an elemental diet continuously, while others may only use elemental formulations until their symptoms subside. If you’re looking to lose weight, an elemental diet may not be the best option.
Before commercial tube feeding products were available, most patients were fed by blending hospital food thin enough to be put through a feeding tube. However, microbial concerns and ease of preparation led to the development of commercially prepared formulas. The first formulas were elemental and introduced in the late 1960s; the first nutrient-intake formula came on the market in 1973. Most early formulas did not contain fiber due to difficulty with flow and clumping issues. The first fiber containing formula came out in 1987, using soy protein (2).
Some further advantages of an elemental diet
Elemental diets are effective in managing the symptoms of inflammatory disorders and digestive system issues. Inflammatory bowel disease can provoke various symptoms that include abdominal pain, low fever, fatigue, weight loss, diarrhea, bloody feces, etc. Within the identification of the environmental risk factors, diet is one of the most important as it regulates intestinal inflammation by modifying the intestinal microbiota, which has an effect on the gastrointestinal permeability (1).
Elemental formulations have already broken down the macronutrients—protein, lipids, and carbohydrates—so your small intestine can easily absorb them. Your bowel, on the other hand, will be able to relax.
Crohn’s disease, which causes chronic inflammation of the digestive system, stomach discomfort, malabsorption, and other problems, has long been treated with an elemental diet. EOE (esophageal eosinophilic esophagitis) is caused by damage to the esophageal lining and results in difficulty swallowing, discomfort, and heartburn. Dietary therapy in EOE consists of elemental and empiric elimination diets. Elemental diet with amino acid-based formula is most effective in achieving disease remission (4).
After four weeks on an elemental diet, 88% of people with EOE no longer had symptoms, according to a study of 21 participants. Inflammation was also reduced significantly as a result of the diet. Small intestinal bacterial overgrowth (SIBO), which is defined by gas and stomach discomfort, may also be treated with elemental diets (4).
An elemental diet’s nutrients are quickly absorbed, so they may not be accessible long enough for your gut bacteria to feed on them, thereby avoiding overgrowth and starving them. Elemental formulations may directly affect bacteria of the GI tract. Early observations of the effect of an elemental diet on stool microflora show that this diet significantly reduces coliforms, enterococci, and bacteroides. The same study showed that the longer subjects were on the diet, the lower the bacterial counts. In a study of 93 persons with SIBO, 85 percent of those who followed a 21-day elemental diet had normal lactulose breath tests. There is a correlation between SIBO and abnormal lactulose breath tests (3).
Furthermore, the symptoms of more than half of individuals who had a normal breath test improved. Last but not least, limited data suggests that an elemental diet may help control the discomfort associated with chronic pancreatitis.
Conclusion
In this brief guide, we answered the query, “Is elemental 028 vegan?” and discussed precautions and dosage recommendations for elemental 028.
References
- Comeche, Jose M., et al. Enteral nutrition in patients with inflammatory bowel disease. Systematic review, meta-analysis, and meta-regression. Nutrients, 2019, 11, 2657.
- Brown, Britta, Kelly Roehl, and Melanie Betz. Enteral nutrition formula selection: current evidence and implications for practice. Nutr Clin Pract, 2015, 30, 72-85.
- Pimentel, Mark, et al. A 14-day elemental diet is highly effective in normalizing the lactulose breath test. Digest dis sci, 2004, 49, 73-77.
- Warners, M. J., B. J. Vlieg-Boerstra, and A. J. Bredenoord. Elimination and elemental diet therapy in eosinophilic oesophagitis. Best Pract Res Clin Gastroenterol, 2015, 29, 793-803.
