Cipcal 500 ingredients

In this brief guide, we will answer the query, “Cipcal 500 ingredients” and will discuss its side effects and dosage to use.

Cipcal 500 ingredients

500 mg of Cipcal Calcium and vitamin D3 are important elements in this tablet, which is utilized as a bone joint supplement. According to the manufacturer’s sheet information, the calcium source of this product is oyster shells and therefore, it is not suitable for vegans.

A study conducted in Italy including 104 men and women showed that only 10.4 % of the sample had a desirable adult Ca intake of minimum 1000 mg/day (1).

What is Cipcal 500?

In the ‘Vitamin’ category, Cipcal-500 Tablet 15s is classified as a drug for treating low levels of calcium in the blood. Several conditions are caused by low calcium levels in the body, such as Vitamin D deficiency, osteoporosis, hypoparathyroidism, latent tetany, and rickets or osteocalcin, which are effectively treated by Cipcal-500. Nutritional deficiencies, malabsorption in the intestine, and lack of sunshine exposure all contribute to Vitamin D insufficiency.

Calcium (mineral) and cholecalciferol (vitamin D3) are both included in Cipcal-500 Tablet 15’s (Vitamin D3). To prevent or cure calcium shortage, people often supplement their diets with the mineral calcium citrate. It gives you all the nutrients you need to keep your bones strong and healthy. 

The loss of bone quality and/or density is a para-physiological phenomenon observed in perimenopause and postmenopause, as well as in other conditions involving aging, inflammatory and/or autoimmune diseases, chronic drug consumption (e.g. glucocorticoids, chemotherapies, etc) and/or nutritional  deficiencies. Data extensively agree with the key role of calcium (Ca) and vitamin D (vitD) supplementation for the prevention of osteopenia/osteoporosis in subjects at a higher risk of fragility fractures and for the treatment of bone strength reduction (1).

Whenever the skin is exposed to UV radiation, a steroid hormone called cholecalciferol is created. It may also be used as a dietary supplement. Following ingestion, it is transformed into a vitamin from a provitamin. Vitamin D in the form of cholecalciferol aids in the maintenance of calcium and phosphorus levels in the blood as well as the mineralization of bones. It’s used to treat and prevent bone diseases including rickets and osteomalacia, among other things.

According to general recommendations, the optimal level of 25(OH) D should be at least ≥ 20 ng/ml to ensure bone health. However, in higher risk subjects, evidence suggests maintaining 25 (OH)D ≥30 ng/ml in order to sustain anti-osteoporotic treatments. Supplementation with cholecalciferol (vitD3) is the most advisable, even during pregnancy and breastfeeding (1).

 Cipcal-500 Tablet 15’s chewable or dissolving tablets may include sugar or aspartame, therefore diabetics and phenylketonurics should exercise care. Before using Cipcal-500 Tablet 15’s, women who are pregnant or breastfeeding should talk to their doctor. Pregnant women should only take higher amounts of vitamin D than the daily recommended amount when instructed to do so by their doctor. If you are nursing, talk to your doctor before taking Cipcal-500 Tablet 15s since it enters into your breast milk. When recommended by a doctor, Cipcal-500 Tablet 15’s are safe for usage in children.

Cipcal-500 Tablet 15’s uses include the treatment of osteoporosis, osteomalacia (Rickets), vitamin D insufficiency, hypocalcemia, and latent tetany.

Benefits to Health

To address low calcium levels in the blood, people use Cipcal-500 Tablet 15’s. Several illnesses are made worse by low calcium levels in the body, such as Vitamin D insufficiency, osteoporosis, hypoparathyroidism, and rickets or osteomalacia. It efficiently addresses all of these. Calcium and cholecalciferol are both included in Cipcal-500 Tablet 15’s (Vitamin D3). 

To prevent or cure calcium shortage, people often supplement their diets with the mineral calcium citrate. It gives you all the nutrients you need to keep your bones strong and healthy. Whenever the skin is exposed to UV radiation, a steroid hormone called cholecalciferol is created. It may also be used as a dietary supplement. Keeping calcium and phosphorus levels in check and bone mineralization is made easier with this supplement.

Calcium is involved in many bodily activities, for instance cellular differentiation, enzymatic activation, neuronal and immune responses. However, the most well-known role of Ca is the regulation of muscle contraction and maintenance of skeletal integrity (1). 

Vitamin D can modulate the innate and adaptive immune responses. Deficiency in Vitamin D is associated with increased autoimmunity as well as an increased susceptibility to infection. As immune cells in autoimmune diseases are responsive to the ameliorative effects of vitamin D, the beneficial effects of supplementing vitamin D deficient individuals with autoimmune disease may extend beyond the effects on bone and calcium homeostasis (2). 

Past evidence based on studies including 3270 women of mean age of 84 ± 6 years, has shown that the association of Ca (1200 mg/day) and vitD (800 IU) reduced the risk of non-vertebral and hip fractures in institutionalized elderly patients. Hence, the efficacy of Ca supplementation in osteopenia/ osteoporosis, seems to be mostly linked to the combination with vitD, due to the synergistic benefits on bone mass density and bone quality of frail patients (1). 

Using Instructions

As an oral tablet, chewable tablet, liquid, and tablet, Cipcal-500 Tablet 15’s are all options.

Tablet/Capsule for extended-release: Drink a glass of water and swallow the pill whole. If your doctor has instructed you to take Cipcal-500 Tablet 15’s regularly, you may do it with or without meals. Do not eat, shatter, or crush it. Depending on the severity of your medical condition, your doctor will determine the appropriate dose for you. Chewable tablet: Chew the chewable tablet of Cipcal-500 Tablet 15 and swallow it whole. Before you consume anything, be sure you’ve chewed it all the way through. Cipcal-500 Tablet 15’s liquid should be measured using a measuring cup and taken according to the doctor’s instructions.

Storage

Keep out of direct sunlight in a cool, dry location.

Side effects

·         Constipation is one of the side effects of taking Cipcal-500 Tablet 15.

·         Irritation in the stomach

In addition, the adverse effects of severe hypercalcemia and hyperphosphatemia induced by exogenous vitamin D supplementation can be detected on most of the organ systems, including the gastrointestinal system, renal system, central nervous system, cardiovascular system, and musculoskeletal system. Studies also described that accidental consumption of 600,000 IU vitamin D2 per day for 21 days resulted in nausea, vomiting, and weight loss, thirst, polyuria, and poor mental concentration in an elderly man (3).

Precautions and Warnings 

Any allergies to Cipcal-500 Tablet 15s or the inactive ingredients should be disclosed to your doctor. If you have hypercalcemia, hypervitaminosis D, or a malabsorption condition, you should not use Cipcal-500 Tablet 15’s (difficulty absorbing nutrition from food). If you have any heart, kidney, liver, or blood vessel diseases, kidney stones, sarcoidosis, Crohn’s disease, Whipple’s disease, achlorhydria, low bile levels, or phosphate imbalance, describe your medical history in detail in your medical history form.

Cipcal-500 Tablet 15’s chewable and dissolving tablets include sugar or aspartame, therefore diabetics and anyone with phenylketonuria should exercise care. Pregnant women should only take higher amounts of vitamin D than the daily recommended amount when instructed to do so by their doctor. When taken by a nursing woman, Cipcal-500 Tablet 15’s are excreted in her milk and should be avoided. Due to the potential for alcohol to interfere with calcium absorption, those using Cipcal-500 Tablet 15s should keep their alcohol consumption under control while doing so. When recommended by a doctor, Cipcal-500 Tablet 15’s are safe for usage in children. Cipcal-500 Tablet 15’s should not be kept above a temperature of 25°C.

Click here to know the mechanism of Cipcal-500

Conclusion

In this brief guide, we answered the query, “Cipcal 500 ingredients” and discussed its side effects and dosage to use.

References

  1. Capozzi, Anna, Giovanni Scambia, and Stefano Lello. Calcium, vitamin D, vitamin K2, and magnesium supplementation and skeletal health. Maturitas, 2020, 140, 55-63.  
  2. Aranow C. Vitamin D and the immune system. J Investig Med. 2011, 59, 881-886.  
  3. Razzaque, Mohammed S. Can adverse effects of excessive vitamin D supplementation occur without developing hypervitaminosis D?. J steroid biochem molec biol, 2018, 180, 81-86.