Can amoxicillin go in the fridge?

In this short guide, we will address the question, “can amoxicillin go in the fridge?” We will also discuss if you have to store amoxicillin in the fridge, the shelf life of amoxicillin, how you should store amoxicillin, and why you should not take amoxicillin after its expiration date.

Can amoxicillin go in the fridge?

Yes, amoxicillin can go in the fridge. A study from the Journal of Applied Pharmaceutical Science demonstrated that refrigerated amoxicillin samples remained more potent than those kept in a cupboard. 

Amoxicillin is a penicillin antibiotic that is used to treat bacterial infections. Middle ear infections, strep throat, pneumonia, skin infections, and urinary tract infections are only a few of them. It is taken orally or, in rare cases, by injection.

Refrigeration is typically not required while using amoxicillin in its capsule or tablet form. Amoxicillin capsules can be kept at room temperature without fear of them losing their effectiveness, but you should store them away from light and heat.

However, it is vital to observe refrigeration guidelines for amoxicillin and other oral suspensions containing amoxicillin. Besides, children’s liquid medications are often flavored which is prone to degradation. Flavored amoxicillin formulations may require refrigeration. 

Do you have to store amoxicillin in the fridge?

Yes, you have to store amoxicillin (the liquid form) in the fridge if you want it to maintain its potency and flavor for longer periods. Another reason to keep amoxicillin suspension in the fridge is that it contains Augmentin, which is highly unstable to heat. 

It is advised that you keep amoxicillin suspension in the fridge, but not in the freezer. Pills and capsules can be kept at room temperature and still be effective in curing sickness. However, the unpleasant smell of amoxicillin pills can be decreased if they are kept in the fridge. 

What is the shelf life of amoxicillin?

The shelf life of amoxicillin varies. This is because there are different amoxicillin products available. A drug’s shelf life is the time span it retains potency. Shelf life starts on the day of the drug’s manufacture. 

Below is a table for you to better understand the shelf life of different forms of amoxicillin:

 Capsules and tabletsSuspensions
StateSolid (or powdered)Liquid (or colloids)
StorageRoom temperatureFridge
Shelf-lifeUp to 1 yearTypically 14 days

How should you store amoxicillin?

Amoxicillin should be stored based on its different forms. Many amoxicillin pills, capsules, and chewable tablets are safe to store at room temperature. But if that particular amoxicillin product (most likely a liquid suspension) must be stored in the refrigerator, the label should state so.

Many antibiotics for children, including amoxicillin, are available as liquid solutions. The pharmacist mixes water with little ground-up particles of medicine (along with flavorings, colourings, stabilizers, and other delights) to form the suspension.

However, if the water’s temperature increases, it can cause certain molecules to degrade. Therefore, such suspensions, particularly amoxicillin and amoxicillin/clavulanate, should be stored in the fridge. As stated on the package insert, keep refrigerated to prolong its shelf life and maintain its potency.

Is it safe to take amoxicillin past its expiry date?

No, it is not safe to take amoxicillin, or any other medication, after the expiry date. There are reasons to avoid taking expired amoxicillin. They are: 

  • It would have lost most if not all of its effectiveness against the disease
  • If the medication fails to kill the disease-causing organisms, it might even help these germs build resistance to the medication. Therefore, the next time you require amoxicillin it may have little or no impact.
  • Taking medications after expiration increases your chances of experiencing side effects associated with the medication. For amoxicillin, common side effects include nausea and rash.

Conclusion

In this short guide, we have addressed the question, “can amoxicillin go in the fridge?” We have also discussed if you have to store amoxicillin in the fridge, the shelf life of amoxicillin, how you should store amoxicillin, and why you should not take amoxicillin after its expiration date.

Hope you found this blog useful. If you have any questions, please let us know.

Citations   

https://pubmed.ncbi.nlm.nih.gov/3400652/#:~:text=Amoxicillin%20trihydrate%20was%20stable%20for,syringes%20at%205%20degrees%20C. https://www.healthline.com/health/amoxicillin-shelf-life#safety-after-expiration

Was this helpful?

Thanks for your feedback!